Motor neuronopathy with dropped hands and downbeat nystagmus: A distinctive disorder? A case report |
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| Authors: | Nimish J Thakore Erik P Pioro Janet C Rucker R John Leigh |
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| Institution: | (1) Department of Neurology, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109, USA;(2) Department of Neurology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA;(3) Department of Neurology, Rush University, 1725 West Harrison, Chicago, IL 60612, USA;(4) Department of Neurology, Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, OH 44106, USA;(5) Department of Neurology, University Hospitals, 11100 Euclid Avenue, Cleveland, OH 44106, USA;(6) Department of Neurology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA |
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| Abstract: | Background Eye movements are clinically normal in most patients with motor neuron disorders until late in the disease course. Rare patients
are reported to show slow vertical saccades, impaired smooth pursuit, and gaze-evoked nystagmus. We report clinical and oculomotor
findings in three patients with motor neuronopathy and downbeat nystagmus, a classic sign of vestibulocerebellar disease. |
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