Antimicrobial effect of tetramethyldithiooxamide and its application as a biocide |
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| Authors: | SV Tabakova TV Kantardjiev VV Mircheva |
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| Institution: | Institute of Molecular Biology, The Bulgarian Academy of Sciences;, National Centre of Infectious and Parasitic Diseases;, and Institute of Polymers, The Bulgarian Academy of Sciences, Sofia, Bulgaria |
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| Abstract: | Tetramethyldithiooxamide (TMDTOA) is a stable and effective inhibitor of metal corrosion. The antimicrobial effects of TMDTOA and its metal compounds were investigated with regard to their use as biocides for water treatment. Growth of a variety of strains of bacteria and yeasts was completely inhibited at 400 υmol 1−1 TMDTOA or its metal complexes. At 100 mg 1−1 there was a 99·99% reduction in the number of viable micro-organisms; this activity persisted for 1–3 months. TMDTOA can be produced cheaply at 98% purity by a novel method, representing an alternative cost-effective water treatment agent combining corrosion-inhibiting and biocide characteristics. |
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