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银杏酸单体的合成及构效关系研究进展
引用本文:张裴,刘前,童元峰,吴松.银杏酸单体的合成及构效关系研究进展[J].天然产物研究与开发,2010,22(2).
作者姓名:张裴  刘前  童元峰  吴松
作者单位:中国医学科学院,北京协和医学院药物研究所卫生部天然药物生物合成重点实验室,北京,100050
摘    要:银杏酸的研究已经成为继银杏黄酮和内酯后的热点.本文综述了银杏酸同系物的结构及部分单体的合成研究进展,分析了合成路线,讨论了各合成方法的特点及适用性,并总结了银杏酸的结构和部分药理活性的关系.

关 键 词:银杏酸单体  合成  构效关系  综述

Progress on the Synthesis and Structure-Activities of Ginkgolic Acids
ZHANG Pei,LIU Qian,TONG Yuan-feng,WU Song.Progress on the Synthesis and Structure-Activities of Ginkgolic Acids[J].Natural Product Research and Development,2010,22(2).
Authors:ZHANG Pei  LIU Qian  TONG Yuan-feng  WU Song
Institution:ZHANG Pei,LIU Qian,TONG Yuan-feng,WU SongInstitute of Materia Medica,Chinese Academy Sciences Peking Union Medical College,Rey Laboratory of Biosynthesis of Natural Prodacts,Ministry of Health of PRC,Beijing 100050,China
Abstract:In this paper ,the recent advances in the synthesis of a series of ginkgolic acids which were extracted from Ginkgo biloba were reviewed.The characteristic and applicability of each synthetic route were clarified .The correlation between the structure and some biological activities were briefly discussed.
Keywords:ginkgolic acids  synthesis  structure and activities  review
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