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Structural and functional basis of mammalian microRNA biogenesis by Dicer
Affiliation:1. CEITEC-Central European Institute of Technology, Masaryk University, 625 00 Brno, Czech Republic;2. National Centre for Biomolecular Research, Faculty of Science, Masaryk University, 625 00 Brno, Czech Republic;3. Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Videnska 1083, 142 20 Prague 4, Czech Republic;4. Centre for Regenerative Medicine, Institute for Regeneration and Repair, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK;5. European Molecular Biology Laboratory (EMBL), Mouse Biology Unit, Via Ramarini 32, Monterotondo Scalo 00015, Italy;6. Bioinformatics Group, Department of Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia;7. Czech Centre for Phenogenomics and Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Prumyslova 595, 252 50 Vestec, Czech Republic;8. Institute of Science and Technology Austria (ISTA), Am Campus 1, 3400 Klosterneuburg, Austria;9. Wellcome Centre for Cell Biology, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK
Abstract:
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  • Keywords:Dicer  helicase  DExD  miRNA  cryo-EM  mirtron  dsRNA  RNAi  dsRBD  TARBP2  PKR
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