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Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
Affiliation:1. Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark;2. Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark;3. Novo Nordisk Foundation for Stem Cell Biology, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark;4. The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark;5. Cell Biology Program and Center for Epigenetics, Memorial Sloan Kettering Cancer Center, New York, NY, USA;6. SciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solna, Sweden
Abstract:
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  • Keywords:transposable elements  retrotransposons  RNA decay  RNA exosome  NEXT complex  HUSH complex
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