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HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
Affiliation:1. Division of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA;2. Department of Molecular Medicine, the University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3904, USA;3. School of Cancer and Pharmaceutical Science, King’s College London, London SE5 9NU, UK;4. Department of Hematology, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China;5. Department of Hematology and Oncology, The Affiliated Zhongda Hospital, Southeast University Medical School, Nanjing 21009, China;6. Division of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA;7. Department of Cell System & Anatomy, the University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3904, USA;8. Mays Cancer Center, Joe R. & Teresa Lozano Long School of Medicine, the University of Texas Health Science Center at San Antonio, San Antonio, TX 78229-3904, USA;9. Department of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA;10. Penn State Cancer Institute, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA;11. Department of Haematological Medicine, King''s College Hospital, London SE5 9RS, UK
Abstract:
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