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TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch
Institution:1. Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA;2. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Abstract:
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  • Keywords:telomere  ALT  alternative lengthening of telomeres  BIR  break-induced replication  TERRA  RAD51AP1  RAD52  R-loop  D-loop  G-quadruplexes  G4  DNA-RNA hybrids  RNaseH1
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