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Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216
Affiliation:1. Ubiquitin Signalling Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia;2. Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia
Abstract:
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  • Keywords:Gordon-Holmes syndrome  neurodegeneration  RNF216  ubiquitin  E3 ligases  allostery  RBR  structural biology  phosphorylation  zinc finger
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