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Cas11 enables genome engineering in human cells with compact CRISPR-Cas3 systems |
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| Affiliation: | 1. Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA;2. State Key Laboratory of Natural Medicines, Department of Pharmacology, China Pharmaceutical University, Nanjing, China;3. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA |
| Abstract: |  |
| Keywords: | CRISPR gene editing Cascade Cas3 Cas11 DNA targeting crRNA large deletion genome engineering |
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