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The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma
Affiliation:1. Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA;2. Broad Institute of MIT and Harvard, Cambridge, MA, USA;3. Harvard/MIT Medical Scientist Training Program, Boston, MA, USA;4. Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;5. Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA;6. Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Abstract:
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  • Keywords:myxoid liposarcoma  MLPS  FUS-DDIT3  fusion oncoprotein  ATP-dependent chromatin remodeling  BAF complex  CEBPB  enhancers  adipogenesis  mesenchymal stem cells
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