EFFECTS OF IONIC STRENGTH OF IMMERSION MEDIUM ON THE STRUCTURE OF PERIPHERAL NERVE MYELIN |
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Authors: | J. B. Finean and P. F. Millington |
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Affiliation: | From the Department of Medical Biochemistry and Pharmacology, University of Birmingham, England |
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Abstract: | A study of the effects of hypertonic solutions on the structure of peripheral nerve myelin reveals an expansion rather than a contraction of the layer spacing. This suggests the absence of "free" water between the myelin layers. Hypotonic solutions bring about a change in radial repeat period from 171 A to 250 to 270 A. These findings are of significance in relation to the structure of myelin. |
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