Effects of Multivitamin/Mineral Supplementation on Trace Element Levels in Serum and Follicular Fluid of Women Undergoing in Vitro Fertilization (IVF) |
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Authors: | Mehmet Okan Özkaya Mustafa Naz?ro?lu Cihan Barak Murat Berkkanoglu |
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Institution: | (1) Department of Obstetrics and Gynecology, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey;(2) Department of Biophysics, Medical Faculty, Suleyman Demirel University, Morfoloji Binasi, Cunur, 32260 Isparta, Turkey;(3) Department of Chemistry, Science Institute, Balıkesir, Turkey;(4) IVF Center of Antalya Private Hospital, Antalya, Turkey; |
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Abstract: | We investigated effects of multivitamin/mineral supplementation on element levels in serum and follicular fluid of women undergoing
IVF. We used three groups in this study. The first group was used as an age-matched and nonpregnant control (n = 13). Group 2 (n = 30) constituted the IVF group and women in the third group who were undergoing IVF also received a multivitamin/mineral
tablet daily for 45 days. Follicular fluid and serum selenium and zinc levels and follicular fluid copper levels were lower
in IVF patients than in controls although follicular fluid aluminum and iron levels were higher in IVF patients than in controls.
However, follicular fluid and serum aluminum, copper, zinc and selenium levels, and serum magnesium levels were higher in
the multivitamin/mineral group than in the IVF group although follicular fluid iron levels were lower in the multivitamin/mineral
group than in the IVF group. In conclusion, we observed that copper, zinc, and selenium in serum and follicular fluid decreased
in women undergoing IVF. Multivitamin/mineral supplementation in serum and follicular fluid of women undergoing IVF normalized
the trace element levels. |
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