Effects of Formaldehyde Inhalation on Zinc,Copper and Iron Concentrations in Liver and Kidney of Male Rats |
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Authors: | Oğuz Aslan Özen Ilter Kus Sezgin Bakirdere Mustafa Sarsilmaz Mehmet Yaman |
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Institution: | (1) Department of Anatomy, Faculty of Medicine, Namık Kemal University, Tekirdağ, Turkey;(2) Department of Anatomy, Faculty of Medicine, Fırat University, Elazığ, Turkey;(3) Chemistry Department, Sciences Faculty, Middle East Technical University, Ankara, Turkey;(4) Chemistry Department, Sciences Faculty, Zonguldak Karaelmas University, Zonguldak, Turkey;(5) Chemistry Department, Sciences and Arts Faculty, Firat University, Elazig, Turkey; |
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Abstract: | In the present study, adult Wistar albino male rats were exposed to formaldehyde at different periods (subacute and subchronic)
and concentrations (5.0 and 10.0 ppm) in order to figure out the changes in the concentration of Zn, Cu and Fe. It was observed
that the formaldehyde inhalation caused gradual decline of body weights in the experimental groups when compared with control
groups. It was found that subacute (4-week) or subchronic (13-week) exposure to formaldehyde for rats may cause growth retardation.
After inhalation procedure, concentration of copper, zinc and iron were determined in liver and kidney tissues of rats using
atomic absorption spectrophotometer. In addition, concentrations of Cu, Zn and Fe changed by the effect of formaldehyde in
subacute and subchronic groups. |
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Keywords: | |
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