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Theoretical and experimental study of the membrane pore effect on the amplitude-frequency dependence of polarizability of a cell
Authors:V. M. Generalov  T. S. Bakirov  A. G. Durymanov  A. V. Pak  E. P. Sukhenko  M. V. Kruchinina  S. A. Kurilovich  I. S. Andreeva  N. I. Pechurkina
Affiliation:(1) Vector State Research Center of Virology and Biotechnology, Koltsovo, Novosibirsk Region, 630559, Russia;(2) Engineering Center of OAO Izhevskii Motozavod Axion-Holding, ul. Gor’kogo 90, Izhevsk, Udmurt Republic, 426000, Russia;(3) Scientific Research Institute of Internal Medicine, Siberian Division, Russian Academy of Medical Sciences, ul. Bogatkova 175/1, Novosibirsk, 630089, Russia
Abstract:The amplitude-frequency dependence of the polarizability of erythrocytes, yeast cells, and latex particles in the range of 1–106 Hz was studied by the method of dielectrophoresis (DEP). Positive DEP of erythrocytes and yeast cells in a frequency range of 60–100 Hz was revealed. The positive DEP of cells in the given range is theoretically explained by appearance of a great number of transverse pores through the membrane and wall of the cell.
Keywords:dielectrophoresis  cell  yeasts  membrane  pore
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