Further alkaloids of Alstonia muelleriana |
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Authors: | David E. Burke Gloria A. Cook James M. Cook Kathleen G. Haller Harvey A. Lazar Philip W. Le Quesne |
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Affiliation: | Department of Chemistry, University of Michigan, Ann Arbor, Michigan, MI 48104, U.S.A. |
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Abstract: | Five further alkaloids, des-N′a-methylanhydromacralstonine, quebrachidine, vinervinine, pleiocarpamine, and 2,7-dihydropleiocarpamine, have been isolated from Alstonia muelleriana bark. Phytochemical problems in the genus Alstonia are considered, especially with reference to the ‘macroline-derived’ indole and bis-indole alkaloids. |
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Keywords: | Apocynaceae bisindole alkaloids macroline unit biomimetic synthesis. |
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