牛蛙视网膜诱导型一氧化氮合酶免疫组化定位

用免疫组织化学方法研究了诱导型一氧化氮酶（iNOS)在牛蛙视网膜中的表达。结果显示，在正常状态视网膜中，无长突细胞呈弱阳性反应；节细胞层、双极细胞，水平细胞和光感受器内段呈阴性反应，在暗适应状态下，神经节细胞，内核层的无长突细胞呈强阳性反应；一些双极细胞，水平细胞和光感受器内段呈弱阳性反应，提示NO主要在暗适应状态下参与视网膜的信息传递过程。

Localization of Inducible Nitric Oxide Synthase in Bullfrog retina

The immunohistochemical method was used to study the expression of Inducible nitric oxide synthase (iNOS) in the bullfrog retina. In normal retina, amacrine cells were weakly labeled, ganglion cells, bipolar cells, horizontal cells and the inner segments of photoreceptors were negative. In dark adaptive retina, both ganglion cells and amacrine cells in inner nuclear layer showed strong iNOS-like immunoreactivity (iNOS-LI), while iNOS-LI was found weakly stained in some bipolar cells, horizontal cells and the inner segments of photoreceptors. The result indicates that NO might participate in visual signal processes mostly at the dark adaptation.