Neurotransmission: emerging roles of endocannabinoids |
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Authors: | Kreitzer Anatol C |
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Institution: | Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305, USA. |
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Abstract: | Postsynaptic release of endocannabinoids can inhibit presynaptic neurotransmitter release on short and long timescales. This retrograde inhibition occurs at both excitatory and inhibitory synapses and may provide a mechanism for synaptic gain control, short-term associative plasticity, reduction of synaptic crosstalk, and metaplasticity. |
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