Neolignans from Nectandra puberula |
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| Affiliation: | 1. Center of Natural Sciences and Humanities, Federal University of ABC, Santo Andre, São Paulo 09210-180, Brazil;2. Institute of Food Chemistry, Technische Universität Braunschweig, Braunschweig, 38106, Germany;3. Center of Parasitology and Mycology, Adolfo Lutz Institute, São Paulo 01246-902, Brazil;4. Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of São Paulo, Diadema, São Paulo 09972-270, Brazil;5. LabMol, Laboratory for Molecular Modeling and Drug Design, Faculty of Pharmacy, Federal University of Goias, Goiânia, Goiás 74605-170, Brazil;1. Grupo de Pesquisa em Produtos Naturais, Núcleo de Ciências Exatas e Tecnológicas, Universidade de Franca, Avenida Dr. Armando Salles de Oliveira, 201, 14404-600 Franca, SP, Brazil;2. Escola de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Avenida do Café s/n, 14040-903 Ribeirão Preto, SP, Brazil;3. National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, and Department of Pharmacognosy, School of Pharmacy, University of Mississippi, University, MS 38677, USA;4. Departamento de Física e Química, Faculdade de Engenharia, Universidade Estadual Paulista, Ilha Solteira-SP, Brazil;5. IF Suldeminas, Avenida Maria da Conceição Santos, 900 - Parque Real, Pouso Alegre - MG, 37550-000, Brazil;1. Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, 100193, Beijing China;2. School of Chinese Materia Medica, Beijing University of Chinese Medicine, 100029, Beijing, China |
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| Abstract: | The trunk wood of Nectandra puberula was found to contain 1,6-geranylgeranodioic acid besides five neolignans, the known veraguensin and the novel 7-hydroxy- and 7-oxo-3,4,3′,4′-tetraoxy-8.8′-neolignans, all with the (8S,8′R)-absolute configuration. |
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