Alkaloids of zephyranthes flava |
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| Affiliation: | 1. The Chinese University of Hong Kong, Shatin, Hong Kong, China;2. Nankai University, Tianjin, China;3. King’s College London, London, United Kingdom;4. Vita Green Health Products (HK) Ltd, Tai Po, Hong Kong, China;5. Hong Kong Institute of Medical Research, Central, Hong Kong, China;6. Genning Partners Company Limited, Causeway Bay, Hong Kong, China |
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| Abstract: | From fresh, mature seeds of Zephyranthes flava, two new 2-oxyphenanthridinium alkaloids, zefbetaine and zeflabetaine along with 15 known free and glucosyloxy alkaloids have been isolated by gradient solvent extraction, chromatography and derivatization. The new compounds have been characterized by comprehensive spectroscopic analyses, chemical transformations and synthesis. Additionally, changes in the major alkaloids during development of the fruits have been analysed and their biological significance appraised. |
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