Dimeric guaianolides and other constituents from Gochnatia species |
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| Institution: | 1. Departamento de Quimica, I.T.E.S.M., Monterrey, Mexico;2. Smithsonian Institution, Department of Botany, Washington, DC 20560, U.S.A.;1. Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, PR China;2. Beijing Institute of Brain Disorders & Research Center for Brain Disorders, Capital Medical University, Beijing, 100069, PR China;3. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, PR China;4. State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Center for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, PR China;1. Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio B-1, Ciudad Universitaria, Morelia, Michoacán 58030, Mexico;2. Université de Versailles Saint-Quentin-en-Yvelines, ILV, UMR CNRS 8180, 45, Avenue des Etats-Unis, 78035 Versailles, France;1. School of Pharmaceutical Sciences, Nanjing Tech University, No.30 South Puzhu Road, Pukou District, 211816, Nanjing, PR China;2. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, No.30 South Puzhu Road, Pukou District, 211816, Nanjing, PR China;3. College of Food Science and Light Industry, Nanjing Tech University, No.30 South Puzhu Road, Pukou District, 211816, Nanjing, PR China;4. Jiangsu National Synergetic Innovation Center for Advanced Materials, 30 Puzhunan Road, Nanjing 211816, Jiangsu, PR China;1. Department of Chemistry, Faculty of Mathematics and Natural Sciences, Padjadjaran University, Jatinangor 45363, Indonesia;2. Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 59100, Malaysia;3. Division of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Gakuen-cho, Sakai, Osaka 599-8531, Japan;1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, People''s Republic of China;2. School of Pharmacy, Lanzhou University, Lanzhou, 730000, People''s Republic of China |
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| Abstract: | The roots of Gochnatia polymorpha afforded two new bisabolene derivatives and four dimeric guaianolides, two of them being isolated previously from G. paniculata. The aerial parts gave two further dimeric guaianolides. The aerial parts of G. hypoleuca afforded three new germacran-8,12-olides, a germacranolide acid and four additional dimeric guaianolides, which may be characteristic for this genus, while the presence of oxygenated germacranolides seems to be typical for the whole subtribe. |
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