Sesquiterpene lactones from Mikania species |
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| Affiliation: | 1. Metabolomics and Mass Spectrometry Research Group, Amazonas State University - UEA, 690065-130 Manaus, AM, Brazil;2. Department of Chemistry, Federal University of Amazonas - UFAM, 69080-900 Manaus, AM, Brazil;3. Faculty of Pharmacy, Federal University of Amazonas - UFAM, 69077-000 Manaus, AM, Brazil;4. School of Biological and Environmental Sciences, Federal University of Grande Dourados - UFGD, 79825-900 Dourados, MS, Brazil;5. Institute of Chemistry, University of Campinas - UNICAMP, 13083-970 Campinas, SP, Brazil |
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| Abstract: | The aerial parts of Mikania guaco afforded in addition to a known eudesmanolide three new ones. The aerial parts of M. vitifolia gave two guaianolides, both being 3-chlorodehydroleudocin derivatives and a seco-germacranolide related to pycnolide. The structures were elucidated by highfield NMR techniques. The proposed position of the hydroxyl group in a chloroguaianolide from a Lasiolaena species has to be revised. |
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