Anticancer and antimicrobial glycosides from ipomoea bahiensis |
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Institution: | 1. Department of Food Science and Technology, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato-ku, 108-8477 Tokyo, Japan;2. Kyoto Prefectural University, Kyoto 606-8522, Japan;3. School of Natural Sciences and Health, Tallinn University, Narva mnt 29, 10120 Tallinn, Estonia;4. National Institute of Oceanography and Fishers, Egypt;1. Key Laboratory of Marine Genetics and Breeding (Ocean University of China), Ministry of Education, Qingdao 266003, China;2. School of Marine Science and Fisheries, Jiangsu Ocean University, Lianyungang 222005, China;1. College of Plant Protection, Shenyang Agricultural University, No. 120 Dongling Road, Shenhe District, Shenyang City 110866, People''s Republic of China;2. Institute of Cereal and Oil Crops, Hebei Academy of Agriculture and Forestry Sciences, Shijiazhuang, Hebei 050035, People''s Republic of China |
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Abstract: | Four new antimicrobial glycosides have been isolated from Ipomoea bahiensis. Spectroscopic properties and basic and acidic hydrolysis characterized them as derivatives of 11 -hydroxy hexadecanoic and 11-hydroxy tetradecanoic acid, glycosidically linked in the 11-position to a trisaccharide unit composed of glucose, rhamnose and fucose which is esterified by tiglic and 3-hydroxy-2-methylbutyric acid. One of these compounds revealed significant activity against Sarcoma 180 in mice. |
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