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Diminishing return for mechanistic therapeutics with neurodegenerative disease duration?
Authors:David C Rubinsztein  Harry T Orr
Institution:1. Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK;2. Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN, USA;3. Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA
Abstract:
Keywords:Huntington's disease  neurodegeneration  point of no return  spinocerebellar ataxia type 1  therapy
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