Quantifying intraclass correlations for count and time‐to‐event data |
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Authors: | Izabela R. C. Oliveira Geert Molenberghs Clarice G. B. Demétrio Carlos T. S. Dias Suely R. Giolo Marcela C. Andrade |
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Affiliation: | 1. Department of Exact Sciences, Federal University of Lavras, Brazil;2. I‐BioStat, Universiteit Hasselt, Belgium;3. Department of Exact Sciences, ESALQ/USP, Brazil;4. I‐BioStat, KU Leuven, Belgium;5. Department of Statistics, Federal University of Paraná, Brazil;6. Department of Biology, Federal University of Lavras, Brazil |
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Abstract: | The intraclass correlation is commonly used with clustered data. It is often estimated based on fitting a model to hierarchical data and it leads, in turn, to several concepts such as reliability, heritability, inter‐rater agreement, etc. For data where linear models can be used, such measures can be defined as ratios of variance components. Matters are more difficult for non‐Gaussian outcomes. The focus here is on count and time‐to‐event outcomes where so‐called combined models are used, extending generalized linear mixed models, to describe the data. These models combine normal and gamma random effects to allow for both correlation due to data hierarchies as well as for overdispersion. Furthermore, because the models admit closed‐form expressions for the means, variances, higher moments, and even the joint marginal distribution, it is demonstrated that closed forms of intraclass correlations exist. The proposed methodology is illustrated using data from agricultural and livestock studies. |
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Keywords: | Generalized linear mixed model ICC Overdispersion Poisson distribution Weibull distribution |
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