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Degradation of 4,9-dichlorodibenzodioxin in rat liver microsomes |
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| Authors: | Sumbaev V V |
| Affiliation: | I. I. Mechnikov Odessa State University. inna@farlep.net |
| Abstract: | The rat liver microsomal cytochrome P 450 was established to dechlorinate 4,9-dichlorodibenzodioxin into 4,9-dihydroxydibenzodioxin. Two isoforms of this cytochrome P 450 were electrophoreticaly identified and quantified. 4,9-dihydroxidibenzodioxin transforms into resorcin with the help of ascorbic acid. |
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