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Diffusion barrier to horseradish peroxidase in the vascular stria of the guinea pig
Authors:Finn Ø Winther
Institution:(1) Anatomical Institute, University of Oslo, Oslo, Norway;(2) The Ear, Nose and Throat Department, Rikshospitalet, Oslo, Norway
Abstract:Summary Guinea pigs were given horseradish peroxidase intracardially and its diffusion in the vascular stria was studied. The Peroxidase spred freely among the intermediate cells and the marginal cells, but was never found to have passed zones occupied by tight junctions. It is concluded that the zones of tight junctions bordering the vascular stria represent a diffusion barrier to horseradish peroxidase.
Keywords:Cochlea  Vascular stria  Guinea pig  Diffusion barrier
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