Alzheimer's disease: clues from flies and worms |
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| Authors: | Anderton B H |
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| Affiliation: | Department of Neuroscience, Institute of Psychiatry, King's College London, UK. |
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| Abstract: | Presenilin mutations give rise to familial Alzheimer's disease and result in elevated production of amyloid beta peptide. Recent evidence that presenilins act in developmental signalling pathways may be the key to understanding how senile plaques, neurofibrillary tangles and apoptosis are all biochemically linked. |
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