Opa-like repeats in the genome of the Medfly Ceratitis capitata |
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Authors: | Inga Sidén-Kiamos Guido Favia Dora Artiaco Giuseppe Saceone Maria Furia Lino C Bolito Christos Louis |
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Institution: | (1) Foundation of Research and Technology-Heilas, Institute of Molecular Biology and Biotechnology, Heraklion, Crete, Greece;(2) Istituto di Biochimica delle Proteine ed Enzimologia, CNR, Napoli, Italy;(3) Departimento di Genetica, Biologia Generale e Molecolare, Universitá di Napoli, Napoli, Italy;(4) Department of Biology, University of Crete, Heraklion, Crete, Greece |
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Abstract: | The sequence determination of several genomic clones isolated from the Mediterranean fruitfly Ceratitis capitata identified the existence of opa-like repeats, often more than one being clustered in small chromosomal segments. These repeats have previously been shown to consist of stretches of tandemly reiterated glutamine-encoding residues, and they are found in multiple genes of several organisms. Most of the repeats described here are flanked or interrupted by stop codons in all reading frames and, thus, could not possibly be part of protein-coding sequences. Furthermore, these repeats, of which there are several hundred in the genome of the Medfly, can be used effectively for the determination of sequence polymorphisms, providing a convenient approach to obtain additional landmarks for the construction of genomic maps of this economically important insect.This paper is dedicated to the memory of our colleague and friend Dr. Jim Flach who took part in the initial phase of this work and died during the course of the investigation. |
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Keywords: | Ceratitis capitata genome structure poly-glutamine DNA polymorphism |
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