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Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds.
Authors:A F Barrero  E J Alvarez-Manzaneda  M M Herrador  R Chahboun  P Galera
Institution:Instituto de Biotecnologia, Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Granada, Spain. afbarre@goliat.ugr.es
Abstract:Efficient syntheses of ent-isozonarol (6a), ent-isozonarone (7a) and ent-chromazonarol (8) from (-)-sclareol (12) are described. 6a and 7a show a significative antitumoral activity.
Keywords:
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