A genetic study of human interferon-alpha-induced repair of DNA damage in hepatitis B patients |
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| Authors: | P L Wang S Y Cong X Y Dong Z C Chen C P Ma |
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| Institution: | Department of Biology, Tsingtao Medical College, People's Republic of China. |
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| Abstract: | In vitro treatment with human interferon-alpha (HuIFN-alpha) of hepatitis B virus-infected peripheral lymphocytes from 17 hepatitis B patients induced a decrease in the frequency of sister-chromatid exchanges (SCE). There was a significant difference in mean SCE frequencies between the HuIFN-alpha-treated patients and the control group, but not between acute and chronic hepatitis B patients treated with HuIFN-alpha. |
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