The synthesis of arginine derivatives of chromone and azauracil |
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Authors: | A. A. Poyarkov M. S. Frasinyuk V. K. Kibirev S. A. Poyarkova |
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Affiliation: | (1) Institute of Bioorganic Chemistry and Oil Chemistry, National Academy of Sciences of Ukraine, ul. Murmanskaya 1, Kiev, 02094, Ukraine |
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Abstract: | The coupling of N-succinimide esters of 3-[7-hydroxy-3-(4-methyl-1,3-thiazol-2-yl)-6-ethyl-4-oxo-4H-chromen-2-yl]propanoic acid and 5-carboxymethyl-6-azauracil with free arginine yielded the corresponding arginine derivatives, which were purified by crystallization. The structures of the compounds were confirmed by 1H NMR spectroscopy |
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Keywords: | arginine azauracil 7-hydroxychromone |
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