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A charge-deficient analogue of spermine with chelating properties |
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| Authors: | Khomutov A R Grigorenko N A Demin A V Vepsalainen J Casero R A Woster P M |
| Abstract: | 1,12-Diamino-3,6,9-triazadodecane, a new isosteric and charge-deficient analogue of spermine, is synthesized. Unlike spermine, the new analogue is an excellent chelator of Cu2+ ions. Possible applications of this compound for studying enzymes of polyamine metabolism and cellular functions of spermine are discussed. The English version of the paper: Russian Journal of Bioorganic Chemistry, 2005, vol. 31, no. 3; see also http://www.maik.ru. |
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