基因治疗在慢性难愈创面的应用进展

众多疾病和创伤都会带来损伤创面的难愈问题，慢性难愈创面的长期存在不仅增加了局部感染的机会，而且大大影响了局部组织的结构和功能。基因治疗作为一种新的生物治疗方法，其相关理论和技术近来日臻完善，为慢性难愈创面的治疗提供了新的技术途径，有望带来突破性的治疗效果。

The Advance of Gene Therapy in Chronic Wound Healing

Population of patients suffering from diabetes,cardiovascular diseases and radiotherapy or chemotherapy have been rising in recent several decades. Chronic wound, which is one of the serious compficafions of above diseases, has become a great challenge to medical sdentists. Constantly chronic wound not only has given an opportunity to local microorganism growth, but also destroyed structure and function of local tissue, which would even affect organs and tissues of the whole body. Traditional therapeutic methods have not produced prominent effects. Gene therapy, of which theory and technology grow increasingly mature as a new biological method, has supplied a novel technique to chronic wound healing and may taken breakthrough to its therapy. We reviewd the present opinions on the pathologic process and gene therapic research of chronic wound.