Decoys 'R' Us: a database of incorrect conformations to improve protein structure prediction |
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Authors: | Samudrala R Levitt M |
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Institution: | Department of Structural Biology, Stanford University School of Medicine, California 94305, USA. ram@csb.stanford.edu |
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Abstract: | The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the function on a set of computer-generated conformations (decoys) to determine whether it can readily distinguish native-like conformations from nonnative ones. We have created "Decoys 'R' Us," a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved. |
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Keywords: | refinement scoring/energy functions |
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