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Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain
Authors:Zhang  Huan  Lu  Ping  Tang  Hui-Ling  Yan   Hua-Juan  Jiang   Wei  Shi   Hang  Chen   Si-Yu  Gao   Mei-Mei  Zeng   Xiang-Da  Long   Yue-Sheng
Affiliation:1.Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Changang East Road, Guangzhou, 510260, China
;2.Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, 510260, China
;
Abstract:Cellular and Molecular Neurobiology - Valproate (VPA), a widely-used antiepileptic drug, is a selective inhibitor of histone deacetylase (HDAC) that play important roles in epigenetic regulation....
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