Valproate-Induced Epigenetic Upregulation of Hypothalamic Fto Expression Potentially Linked with Weight Gain |
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Authors: | Zhang Huan Lu Ping Tang Hui-Ling Yan Hua-Juan Jiang Wei Shi Hang Chen Si-Yu Gao Mei-Mei Zeng Xiang-Da Long Yue-Sheng |
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Affiliation: | 1.Institute of Neuroscience and the Second Affiliated Hospital of Guangzhou Medical University, 250 Changang East Road, Guangzhou, 510260, China ;2.Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou, 510260, China ; |
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Abstract: | Cellular and Molecular Neurobiology - Valproate (VPA), a widely-used antiepileptic drug, is a selective inhibitor of histone deacetylase (HDAC) that play important roles in epigenetic regulation.... |
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