Hst-3: an X-linked hybrid sterility gene |
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| Authors: | J L Guénet C Nagamine D Simon-Chazottes X Montagutelli F Bonhomme |
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| Institution: | Unité de Génétique des Mammifères de l'Institut Pasteur, Paris, France. |
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| Abstract: | A gene, Hst-3, responsible for sterility in F1 males from crosses between Mus spretus and laboratory strains of mice such as C57BL/6, has been localized on the distal part of the X chromosome, using both DNA probes and biochemical markers on a panel of F1(C57BL/6 x SEG) x C57BL/6 backcross males. This gene may be a model for studying mammalian hybrid sterility. |
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