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Recombinant Fragment of the Extracellular Domain of Human Desmoglein 3 Fused with the Fc-Fragment of Human IgG1 Selectively Adsorbs Autoreactive Antibodies from the Sera of Pemphigus Patients |
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| Authors: | Larina E. N. Karasev V. S. Shpilevaya M. V. Aliev T. K. Bochkova O. P. Karamova A. E. Balabashin D. S. Deryabin D. G. Bobik T. V. Smirnov I. V. Kubanov A. A. Staroverov S. M. Gabibov A. G. Kirpichnikov M. P. |
| Affiliation: | 1.Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia ;2.JSC “BioChemMack S&T”, Moscow, Russia ;3.State Research Center of Dermatovenereology and Cosmetology, Moscow, Russia ;4.Moscow State University, Moscow, Russia ; |
| Abstract: | Doklady Biochemistry and Biophysics - Using the recombinant second fragment of the extracellular domain (EC2) of human desmoglein type 3 (Dsg3) as an affinity ligand, an immunosorbent was obtained... |
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