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Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation |
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| Authors: | Sung-Hoon Kim Jung-Hyun Choi Peng Wang Christopher D. Go Geoffrey G. Hesketh Anne-Claude Gingras Seyed Mehdi Jafarnejad Nahum Sonenberg |
| Affiliation: | 1. Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada;2. Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada;3. Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON M5G 1X5, Canada;4. Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A1, Canada;5. Patrick G. Johnston Centre for Cancer Research, Queen’s University Belfast, Belfast BT9 7AE, UK |
| Abstract: |  |
| Keywords: | mTORC1 amino acid Rag GTPases aminoacyl-tRNA synthetase TARS2 threonine |
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