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DNA breaks as triggers for antigenic variation in African trypanosomes |
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| Authors: | Sam Alsford David Horn Lucy Glover |
| Affiliation: | (1) London School of Hygiene &; Tropical Medicine, Keppel Street, London, WC1E 7HT, UK; |
| Abstract: | The DNA repair machinery has been co-opted for antigenic variation in African trypanosomes. New work directly demonstrates that a double-strand break initiates a switch in the expressed variant surface coat. |
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