Synthesis of Novel Isomeric Dideoxydidehydronucleosides |
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Authors: | Vasu Nair Sanjib Bera Travis Mickle Serge Van Calenbergh |
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Institution: | Department of Chemistry , The University of Iowa , Iowa City, Iowa, 52242, U.S.A. |
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Abstract: | Abstract Methodologies for the synthesis of novel isomeric dideoxynucleosides with unsaturation in the carbohydrate moiety have been developed. An example of the synthesis (Isod4A) is presented. Antiviral studies are in progress. |
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