Synthesis of Ring-Expanded Xanthines and Xanthosines Containing the Imidazo[4,5-d][1,3]diazepine Ring System |
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Authors: | Ramachandra S Hosmane Vijayvithal P Vaidya Mi Kyung Chung Upali Siriwardane Hongming Zhang Narayan S Hosmane |
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Institution: | 1. Laboratory for Chemical Dynamics Department of Chemistry and Biochemistry , University of Maryland Baltimore County Baltimore , Maryland, 21228;2. Department of Chemistry , Southern Methodist University , Dallas, Texas, 75275 |
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Abstract: | Abstract Syntheses of 4, 5, 6, 8-tetrahydro-1H, 7H-imidazo4, 5-d] 1, 3]-diazepine-5, 8-dione (9), its 3-benzyl derivative (8), and 3- and 1-ribosyl derivatives, (12) and (13), respectively, are reported. Single-crystal x-ray analyses of 8 and 9 are also presented. |
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