A New and Convenient Approach for the Synthesis of Ribo- and 2′-Deoxyribo-β-L-Furanonucleosides Starting From β-L-Xylofuranonucleosides |
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Authors: | V Boudou G Gosselin J-L Imbach |
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Institution: | Laboratoire de Chimie Bioorganique , Université des Sciences et Techniques du Languedoc , UMR CNRS-USTL 5625, 34095, Montpellier Cedex 5, France |
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Abstract: | Abstract Ribo- and 2′-deoxyribo-β-L-furanosyladenine have been synthesized. Although these compounds have been already reported in the literature, it seemed to us that a more convenient approach for their synthesis deserved to be developed. Intramolecular substitution as well as Mitsunobu reaction were used to invert the configuration of carbon 3′ of starting β-L-xylofuranosyl intermediates. |
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