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A New Cyclic Phosphoramidate D4T Prodrug Approach cycloAmb-D4T-Phosphoramidates |
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| Authors: | Martina Lorey Chris Meier |
| Affiliation: | Institut für Organische Chemie, Universit?t Hamburg , Martin-Luther-King-Platz 6, D-20146, Hamburg, Germany |
| Abstract: | Abstract A new potential phosphoramidate prodrug approach for d4T 1 is described. In hydrolyses studies the cycloAmb-d4T-phosphoramidates 2 and 3 proved to deliver d4TMP following a tandem reaction. |
| Keywords: | |