Synthesis of a Carboxamide Linked UBr∗UBr Dimer–Duplex and Triplex Stabilities of the Corresponding Oligodeoxynucleotides |
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| Authors: | Abdel Aleem H Abdel Aleem Erik Larsen Erik B Pedersen |
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| Institution: | Department of Chemistry , Odense University , DK-5230, Odense M, Denmark |
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| Abstract: | Abstract A UBr?UBr dimer was synthesized by connecting the appropiate nucleoside monomers through a 5-atom carboxamide linkage. The dimer was incorporated in oligodeoxynucleotides and investigated for hybridization properties toward single and double stranded DNA. |
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