Enzyme Aided Regioselective Acylation of Nucleosides |
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Authors: | Shoichiro Ozaki Kayoko Yamashita Takako Konishi Takahiro Maekawa Mitsuaki Eshima Atsuliiko Uemura |
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Affiliation: | Department of Applied Chemistry, Faculty of Engineering , Ehime University , Matsuyama, 790, Japan |
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Abstract: | Abstract Selective protection of the three hydroxyl groups of sugar moiety of nucleosides have been studied by enzyme-catalyzed esterification in organic solvents. Selectively protected products were obtained. The reaction provides an efficient method for selective protection of nucleosides. |
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