Novel Analogues of Tiazofurin by Lawesson Reagent Effected Cyclization |
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| Authors: | Bozenna Golankiewicz Piotr Januszczyk |
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| Affiliation: | Institute of Bioorganic Chemistry, Polish Academy of Sciences ul , Noskowskiego, 12/14, 61-704, Poznań, Poland |
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| Abstract: | Abstract 2-Benzylthiazole-4-carboxamide 4 and 5-(β-D-ribofuranosylamino) thiazole-4-carboxamide 10 were synthesized from phenylacetylamino- and formylamino cyanoacetic acid esters 1a and 1b, respectively. The ribosylation reaction leading to 10 gave rise also to its α anomer as a minor product. |
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