|
|||||
|
|
Synthesis and Antiviral Activity of Some N-Pentopyranosyl-2-Pyridinethiones |
|
| Authors: | Adel M E M Attia Elsayed I Ibrahim Fouad E A Hay Mohammed M A Abbasi Hanaa A E Mansour |
| Institution: | 1. Chemistry Department, Faculty of Education , Tanta University (Kafr El-Sheikh Branch) , Egypt;2. Chemistry Department, Faculty of Science , Suez Canal University , Egypt;3. Chemistry Department, Faculty of Science , Tanta University , Egypt |
| Abstract: | Abstract A novel synthesis of 1-(β-D-pentopyranosyl)pyridinethione nucleosides utilizing pyridine-2(1H)-thiones and α-bromoxylose or β-bromoarabinose triacetate as starting components is described. The free nucleosides were tested for their potential activity against HIV and different types of tumor virus. |
| Keywords: | |