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Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A |
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| Authors: | Motoyuki Sugai Kaoru Ooku Tomoko Akiyama Shingo Inoue Shigemitsu Iseda Yoichiro Miyake Hidekazu Suginaka |
| Affiliation: | Department of Microbiology, Hiroshima University School of Dentistry, Japan. |
| Abstract: | The effect of cibacron blue 3G-A (CB) on bacteriolysis induced by penicillin G was investigated using Staphylococcus aureus FDA 209P. Penicillin-induced lysis was completely inhibited by 30 microM CB. However, the bactericidal effect of penicillin G was not influenced by CB. These results indicate that a bacteriolytic process is not essential for penicillin to kill S. aureus. |
| Keywords: | Cibacron blue Autolysin Staphylococcus aureus Penicillin |