| 刺激和损毁下丘脑室旁核对针刺镇痛的影响 |
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| 引用本文： | 杨俊,宋朝佑.刺激和损毁下丘脑室旁核对针刺镇痛的影响[J].生理学报,1992,44(5):455-460. |
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| 作者姓名： | 杨俊 宋朝佑 |
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| 作者单位： | 第二军医大学神经生物学教研室，第二军医大学神经生物学教研室，第二军医大学神经生物学教研室，第二军医大学神经生物学教研室 上海 200433 广州南方医院核医学科 510515，上海 200433，上海 200433，上海 200433 |
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| 摘 要： | 本文采用脑刺激和损毁法,探讨了大鼠下丘脑室旁核(PVH)在针刺镇痛中的作用。结果表明:电刺激PVH及PVH内微量注射谷氨酸钠均可增强“足三里”的针刺镇痛效果,呈量效关系;电解损毁PVH则削弱针刺镇痛效果;去除脑下垂体不能抑制PVH内注射谷氨酸钠的作用。
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| 关 键 词： | 针刺镇痛 下丘脑 室旁核 |
EFFECTS OF STIMULATION AND CAUTERIZATION OF HYPOTHALAMIC PARAVENTRICULAR NUCLEUS ON ACUPUNCTURE ANALGESIA |
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| YANG JUN,SONG CHAO-YOU,LIN BAO-CHENG,ZHUR HE-NIAN.EFFECTS OF STIMULATION AND CAUTERIZATION OF HYPOTHALAMIC PARAVENTRICULAR NUCLEUS ON ACUPUNCTURE ANALGESIA[J].Acta Physiologica Sinica,1992,44(5):455-460. |
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| Authors: | YANG JUN SONG CHAO-YOU LIN BAO-CHENG ZHUR HE-NIAN |
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| Institution: | Department of Neurobiology, Second Military Medical College, Shanghai. |
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| Abstract: | The role of hypothalamic paraventricular nucleus (PVH) in acupuncture analgesia was investigated by local brain stimulation and cauterization. Theresults showed that electrical or L-glutamate sodium stimulation of PVH couldenhance the effect of analgesia of Zusanli acupuncture, both in a dose dependentmanner. Electrical cauterization of PVH decreased the effect of acupunctureanalgesia, while removal of pituitary had no effect on the enhancing effect byL-glutamate sodium injection. |
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| Keywords: | hypothalamic paraventricular nucleus acupuncture analgesia |
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