Complete genome sequence of human adenovirus prototype 17 |
| |
Authors: | Dehghan Shoaleh Seto Jason Hudson Nolan R Robinson Christopher M Jones Morris S Dyer David W Chodosh James Seto Donald |
| |
Institution: | School of Systems Biology, George Mason University, Manassas, VA 20110, USA. |
| |
Abstract: | As one of the first five human adenoviruses (HAdVs) to be sequenced, type 17 was important as a reference tool for comparative genomics of recently isolated HAdV pathogens in species D. HAdV-D17 was the first species D adenovirus to be sequenced and was deposited in GenBank in 1999. These genome data were not of high quality, and a redetermination of the same stock virus provides corrected data; among the differences are a length of 35,139 bp versus 35,100 bp in the original, and 160 mismatches to the original genome were found. Annotation of the coding sequences reveals 39 as opposed to 8, a finding which is important for phylogenomic studies. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|